Read a selection of our peer-reviewed publications.

2025

Clinical decision-making and care pathways for people with multiple long-term conditions admitted to hospital: a scoping review

Howe NL, Blackburn E, Sheppard A, Pretorius S, Suklan J, Bellass S, et al. BMJ Open. 2025; 15: e100270.

Can we trust published evidence on point-of-care tests for cholesterol? A rapid review

Mutepfa CC, Hicks TP, Winter A, Dickinson RE, Williams C, Harrison N, et al. BMJ Open. 2025; 15: e080726

ADMISSION – A research collaborative to transform understanding of multiple long-term conditions for people admitted to hospital

Witham MD, Bartle V, Bellass S, Bunn JG, Cartner D, Cordell HJ, et al. Journal of Multimorbidity and Comorbidity. 2025; 15.

Women’s perspectives of molecular breast imaging: a qualitative study

Elliott H, Allen AJ, Forester ND, Graziadio S, Jones WS, Lendrem BC, et al. British Journal of Cancer. 2025; 132(3): 276-282

Mapping decision-making pathways: Determination of intervention entry points for diagnostic tests in suspected serious infection

Naseem R, Howe N, Pretorius S, Willams C, Lendrem C, Pallmann P, et al. [version 2; peer review: 2 approved]. NIHR Open Research. 2025, 4:35

2024

Eliciting required and desired diagnostic test characteristics to develop patient-focused target product profiles (TPPs) for diagnosing infection and exacerbations in cystic fibrosis

Howe N, Takawira C, Naseem R and Green K. [version 1; peer review: 1 approved]. NIHR Open Research. 2024, 4:81

What diagnostic tests are available for respiratory infections or pulmonary exacerbations in cystic fibrosis: A scoping literature review

Naseem R, Howe N, Williams CJ, Pretorius S, Green K. Respiratory Investigation. 2024; 62(5): 817-831

Rapid Assay Diagnostic for Acute Stroke Recognition (RADAR): study protocol for a diagnostic accuracy study

Shaw L, Burgess D, Dixit A, Gaude E, Lendrem C, McClelland G, et al. BMJ Open. 2024; 14: e087130

The impact of the COVID-19 pandemic and associated disruptions in health-care provision on clinical outcomes in people with diabetes: a systematic review

Hartmann-Boyce J, Highton P, Rees K, Onakpoya I, Suklan J, Curtis F, et al. Lancet Diabetes Endocrinology. 2024; 12(2): 132-148

Experiences of hospital care for people with multiple long-term conditions: a scoping review of qualitative research

Bellass S, Scharf T, Errington L, Bowden Davies K, Robinson S, Runacres A, et al. BMC Medicine. 2024; 22(1): 25

2023

An Update to the Overview of Reviews: Risks of and From SARS-COV-2 Infection and COVID-19 in People With Diabetes

Hartmann-Boyce J, Rees K, Onakpoya I, Otunla A, Morris E, Morgan J, et al. Diabetes Care. 2023; 46(12): e215-e216

Mapping inpatient care pathways for patients with COPD: an observational study using routinely-collected electronic hospital record data

Evison F, Cooper R, Gallier S, Missier P, Sayer AA, Sapey E, et al. ERJ Open Research. 2023; 9(5): 00110-2023

Researching multimorbidity in hospital: can we deliver on the promise of health informatics?

Witham MD, Cooper R, Missier P, Robinson SM, Sapey E, Sayer AA. European Geriatric Medicine. 2023; 14(4): 765-768

Sample size determination for point-of-care COVID-19 diagnostic tests: a Bayesian approach

Williamson SF, Williams CJ, Lendrem BC, Wilson KJ. Diagnostic and Prognostic Research. 2023; 7:17

Patient Self-Testing of Kidney Function at Home, a Prospective Clinical Feasibility Study in Kidney Transplant Recipients

Murray JS, Williams CJ, Lendrem C, Smithson J, Allinson C, Robinson J, et al. Kidney International Reports. 2023; 8(6): 1170-1182

A high-resolution melt curve toolkit to identify lineage-defining SARS-CoV-2 mutations

Fraser AJ, Greenland-Bews C, Kelly D,  Williams CT, LSTM Diagnostics Group, CONDOR Steering Group, et al. Science Reports. 2023; 13: 3887

An open source pipeline for quantitative immunohistochemistry image analysis of inflammatory skin disease using artificial intelligence

Ding Y, Dhawan G, Jones C, Ness T, Nichols E, Krasnogor N, Reynolds NJ. Journal of the European Academy of Dermatology and Venereology. 2023; 37: 605–614

Multimorbidity in bronchiectasis: a systematic scoping review

Marsland I, Sobala R, De Soyza A, Witham M. ERJ Open Research. 2023; 9(1): 00296-2022

Remote collection of physical performance measures for older people: a systematic review

Heslop PA, Hurst C, Sayer AA, Witham MD. Age and Ageing. 2023; 52(1): afac327

2022

Perceived feasibility, facilitators and barriers to incorporating point-of-care testing for SARS-CoV-2 into emergency medical services by ambulance service staff: a survey-based approach

Green K, Micocci M, Hicks T, Winter A, Martin JE, Shinkins B, et al. BMJ Open. 2022; 12: e064038

Risks of infection, hospital and ICU admission, and death from COVID-19 in people with asthma: systematic review and meta-analyses

Otunla A, Rees K, Dennison P, Hobbs R, Suklan J, Schofield E et al. BMJ Evidence-Based Medicine. 2022; 27: 263-273

Clinicians’ Perspectives on Barriers and Facilitators for the Adoption of Non-Invasive Liver Tests for NAFLD: A Mixed-Method Study

Vali Y, Eijk R, Hicks T, Jones WS, Suklan J, Holleboom AG, et al.  Journal of Clinical Medicine. 2022; 11(10): 2707

Bayesian sample size determination for diagnostic accuracy studies

Wilson KJ, Williamson SF, Allen AJ, Williams CJ, Hellyer TP, Lendrem BC.  Statistics in Medicine. 2022; 1-15

Diagnosing ventilator-associated pneumonia (VAP) in UK NHS ICUs: the perceived value and role of a novel optical technology

Jones WS, Suklan J, Winter A, Green K, Craven T, Bruce A, et al. Diagnostic and Prognostic Research. 2022; 6(1): 5

Primary Sjögren’s syndrome: longitudinal real-world, observational data on health-related quality of life

Tarn J, Lendrem D, McMeekin P, Lendrem C, Hargreaves B, Ng W-F. Journal of Internal Medicine. 2022; 291: 849–855

Genomic abnormalities of TP53 define distinct risk groups of paediatric B-cell non-Hodgkin lymphoma.

Newman A, Zaka M, Zhou P, Blain A, Erhorn A, Barnard A, et al. Leukemia. 2022; 36: 781–789

2021

Strategies to implement SARS-CoV-2 point-of-care testing into primary care settings: a qualitative secondary analysis guided by the Behaviour Change Wheel

Kierkegaard P, Hicks T, Allen AJ, Yang Y, Hayward G, Glogowska M, Nicholson BD et al. Implementation Science Communications. 2021; 2: 139

Systematic review of studies investigating ventilator associated pneumonia diagnostics in intensive care

Al‑Omari B, McMeekin P, Allen AJ, Akram AR, Graziadio S, Suklan J, Jones WS, et al. BMC Pulmonary Medicine. 2021; 21: 196

 Care pathway and prioritization of rapid testing for COVID-19 in UK hospitals: a qualitative evaluation.

Hicks T, Winter A, Green K, Kierkegaard P, Price DA, Body R, Allen AJ, et al. BMC Health Services Research. 2021; 21: 532

Purines for Rapid Identification of Stroke Mimics (PRISM): study protocol for a diagnostic accuracy study.

Shaw L, Graziadio S, Lendrem C, Dale N, Ford GA, Roffe C, Smith CJ, et al. Diagnostic and Prognostic Research. 2021; 5: 11

Conducting invasive urodynamics in primary care: qualitative interview study examining experiences of patients and healthcare professionals

Milosevic S, Joseph-Williams N, Pell B, Cain E, Hackett R, Murdoch F, Ahmed H, Allen AJ et al. Diagnostic and Prognostic Research. 2021; 5: 10

Utility of Routine Laboratory Biomarkers to Detect COVID-19: A Systematic Review and Meta-Analysis

Suklan J, Cheaveau J, Hill S, Urwin SG, Green K, Winter A, Hicks T, et al. Viruses. 2021; 13(5): 803

Is Point-of-Care testing feasible and safe in care homes in England? An exploratory usability and accuracy evaluation of a Point-of-Care Polymerase Chain Reaction test for SARS-COV-2

Micocci M, Gordon AL, Seo MK, Allen AJ, Davies K, Lasserson D, Thompson C, et al. Age and Ageing. 2021; afab072

Improving the identification of patients with a genetic diagnosis of familial hypercholesterolaemia in primary care: A strategy to achieve the NHS long term plan

Ingoe L, Potter A, Musson S, Neely D, Pilkington G, Allen AJ, Reay D, et al. Atherosclerosis. 2021; 321: 38-45

Comparative diagnostic accuracy studies with an imperfect reference standard – a comparison of correction methods

Umemneku Chikere CM, Wilson KJ, Allen AJ, Vale L. BMC Medical Research Methodology. 2021; 21: 67

COVID-19 testing in English care homes and implications for staff and residents

Micocci M, Gordon AL, Allen AJ, Hicks T, Kierkegaard P, McLister A, et al. Age and Ageing. 2021; afab015

Asthma and COVID-19: review of evidence on risks and management considerations

Hartmann-Boyce J, Gunnell J, Drake J, Otunla A, Suklan J, Schofield E, et al. BMJ Evidence-Based Medicine. 2021; 26: 195

2020

Predicting Postoperative Vision for Macular Hole with Automated Image Analysis

Murphy DC, Nasrulloh AV, Lendrem C, Graziado S, Alberti M, la Cour M, et al. Ophthalmology Retina. 2020; 4(12): 1211-1213

At what times during infection is SARS-CoV-2 detectable and no longer detectable using RT-PCR-based tests? A systematic review of individual participant data

Mallett S, Allen AJ, Graziadio S, Taylor SA, Sakai NS, Green K, et al. BMC Medicine. 2020; 18(1): 346

Unmet clinical needs for COVID-19 tests in UK health and social care settings

Graziadio S, Urwin SG, Cocco P, Micocci M, Winter A, Yang Y, et al. PLoS One. 2020; 15(11): e0242125

The Clinical Need for New Diagnostics in the Identification and Management of Patients with Suspected Sepsis in UK NHS Hospitals: A Survey of Healthcare Professionals

Winter A, Jones WS, Allen AJ, Price DA, Rostron A, Filieri R, et al. Antibiotics (Basel). 2020; 9(11): 737

Cost Consequences for the NHS of Using a Two-Step Testing Method for the Detection of Clostridium difficile with a Point of Care, Polymerase Chain Reaction Test as the First Step

Jones WS, Rice S, Power HM, Maniatopoulos G, Suklan J, Beyer F, et al. Diagnostics (Basel). 2020; 10(10): 819

Diagnostic and economic evaluation of a point-of-care test for respiratory syncytial virus

Allen AJ, Gonzalez-Ciscar A, Lendrem C, Suklan J, Allen K, Bell A, et al. ERJ Open Research. 2020; 6(3): 00018-2020

PRImary care Management of lower Urinary tract Symptoms in men: protocol for development and validation of a diagnostic and clinical decision support tool (the PriMUS study)

Pell B, Thomas-Jones E, Bray A, Agarwal R, Ahmed H, Allen AJ, et al. BMJ Open. 2020; 10(6): e037634

First experience of COVID-19 screening of health-care workers in England

Hunter E, Price DA, Murphy E, van der Loeff IS, Baker KF, Lendrem D, et al. Lancet. 2020; 395(10234): e77-e78

Asymmetrical Bioimpedance in the Anterior Circulation for Urgent Stratification of suspected Stroke (ABACUS Stroke): study protocol for a diagnostic accuracy study

Price CI, Shaw L, Dixit A, Graziadio S, Lendrem C, Mitra D, et al. Diagnostic and Prognostic Research. 2020; 4(2)

How to Ease the Pain of Taking a Diagnostic Point of Care Test to the Market: A Framework for Evidence Development

Graziadio S, Winter A, Lendrem BC, Suklan J, Jones WS, Urwin SG, et al. Micromachines (Basel). 2020; 11(3): 291

High Variability in Sepsis Guidelines in UK: Why Does It Matter?

Bray A, Kampouraki E, Winter A, Jesuthasan A, Messer B, Graziadio S. International Journal of Environmental Research and Public Health. 2020; 17(6): 2026

2019

Efficiency and Health Economic Evaluations of BD OneFlow™ Flow Cytometry Reagents for Diagnosing Chronic Lymphoid Leukemia

Moloney E, Watson H, Barge D, Allen AJ, Carey P, Hislop J, et al. Cytometry Part B Clinical Cytometry. 2019; 96(6): 514-520

A PCR-based diagnostic testing strategy to identify carbapenemase-producing Enterobacteriaceae carriers upon admission to UK hospitals: early economic modelling to assess costs and consequences

Moloney E, Lee KW, Craig D, Allen AJ, Graziadio S, Power M, et al. Diagnostic and Prognostic Research. 2019; 3: 8

Opportunities and challenges of a novel cardiac output response to stress (CORS) test to enhance diagnosis of heart failure in primary care: qualitative study

Charman S, Okwose N, Maniatopoulos G, Graziadio S, Metzler T, Banks H, et al. BMJ Open. 2019; 9(4): e028122

Application of MR-ProADM to predict prevention of hospitalisation, derived from a multi-centre study

Cullinan M, Graziadio S, Price DA. Critical Care. 2019; 23(1): 129

Can mid-regional pro-adrenomedullin (MR-proADM) increase the prognostic accuracy of NEWS in predicting deterioration in patients admitted to hospitalwith mild to moderately severe illness? A prospective single-centre observational study

Graziadio S, O’Leary RA, Stocken DD, Power M, Allen AJ, Simpson AJ, et al. BMJ Open. 2019; 8(11): e020337

Between a ROC and a hard place: Teaching prevalence plots to understand real world biomarker performance in the clinic

Lendrem BC, Lendrem DW, Pratt AG, Naamane N, McMeekin P, Ng WF, et al. Pharmaceutical Statistics. 2019; 18(6): 632-635

Diagnostic test evaluation methodology: A systematic review of methods employed to evaluate diagnostic tests in the absence of gold standard – An update

Umemneku Chikere CM, Wilson K, Graziadio S, Vale L, Allen AJ. PLoS One. 2019; 14(10): e0223832

Early Economic Evaluation of Diagnostic Technologies: Experiences of the NIHR Diagnostic Evidence Co-operatives

Abel L, Shinkins B, Smith A, Sutton AJ, Sagoo GS, Uchegbu I, et al. Medical Decision Making. 2019; 39(7): 857-866

2018

Cost implications for the NHS of using the Alere™ i Influenza A & B near patient test with nasal swabs

Allen AJ, O’Leary RA, Davis S, Graziadio S, Jones WS, Simpson AJ, et al. Diagnostic and Prognostic Research. 2018; 2: 15

Diagnostic accuracy and cost analysis of the Alere™ i Influenza A&B near-patient test using throat swabs

Davis S, Allen AJ, O’Leary R, Power M, Price DA, Simpson AJ, et al. Journal of Hospital Infection. 2017; 97(3): 301-309

Interactive visualisation for interpreting diagnostic test accuracy study results

Fanshawe TR, Power M, Graziadio S, Ordóñez-Mena JM, Simpson J, Allen J. BMJ Evidence Based Medicine. 2018; 23(1): 13-16